This CPB is revised to state that PAP with pressure relief technology (eg, A-Flex, Bi-Flex, C-Flex, C-Flex +) is considered medically necessary DME when criteria are met. This CPB has been revised to state that: (a) the Silent Partner OSA appliance is considered equally effective to standard oral appliances; (b) oral appliances for snoring (e.g., Snore Guard) are considered not medically necessary treatment of disease, as snoring is not considered a disease; and (c) the following are considered experimental and investigational: (i) genetic association studies (e.g., tumor necrosis factor-alpha (TNFA) 308 A/G polymorphism, angiotensin-converting enzyme (ACE) gene insertion/deletion, apolipoprotein E (ApoE) polymorphism) for the diagnosis of obstructive sleep apnea; (ii) epiglottidectomy/partial epiglottidectomy for the treatment of adult obstructive sleep apnea.; and (iii) oral appliances and UPPP for treatment of upper airway resistance syndrome. Indications for obstructive sleep apnea testing are added to the appendix.