This CPB has been revised to state that cardiopulmonary exercise testing is considered experimental and investigational for (i) functional and prognostic evaluation of persons with dystrophinopathies (e.g., Becker muscular dystrophy and Duchenne muscular dystrophy) and multiple sclerosis, (ii) prediction of post-operative morbidity/survival in persons undergoing major surgery (e.g., abdominal aortic aneurysm repair and hepatic resection surgery), and (iii) risk stratification of persons with asymptomatic valve diseases (e.g., aortic stenosis).